Predominant but silent C1q deposits in mesangium on transplanted kidneys - long-term observational study

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Predominant but silent C1q deposits in mesangium on transplanted kidneys - long-term observational study.

BACKGROUND C1q nephropathy (C1qN) was first described as glomerular disease characterized by predominant meangial C1q deposits in patients with proteinuria and no evidence of systemic lupus erythematosus. Several studies, however, revealed the clinical heterogeneity of C1qN, showing some cases with normal urinalysis. To confirm the existence of cases with predominant mesangial C1q deposits and ...

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Long-term clinical outcome of paediatric kidneys transplanted to adults.

BACKGROUND We have earlier shown an increase in the size and excellent graft function of paediatric kidneys transplanted to adults up to 1 year following transplantation. This study was performed to assess the long-term outcome of these transplants. METHODS From a primary cohort of 19 adults, receiving a first kidney transplant from a paediatric donor <10 years of age, 16 patients were availa...

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Oxalate deposits in biopsies from native and transplanted kidneys, and impact on graft function.

BACKGROUND The purpose of this study was to examine the incidence of oxalate deposits in native and renal allograft biopsies, and its impact on graft function. METHODS The renal biopsy files at The Johns Hopkins University between 2000 and 2006 were searched to identify biopsies with oxalate deposits, determine the density of oxalate deposits in renal graft biopsies, compare graft histology a...

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Long-term outcome of highly sensitized African American patients transplanted with deceased donor kidneys.

Undertaking transplantation in highly sensitized African American (AA) patients as transplant recipients represents a unique challenge. We retrospectively compared the outcomes of AA with non-African American (NAA) patients who had panel reactive antibody >80% and received deceased donor (DD) kidneys by virtual crossmatch. Immunosuppressive regimen included basiliximab induction and tacrolimus,...

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Long Term Follow-up of Human Transplanted Kidneys by DWI and BOLD Imaging

Introduction: Previously, we determined short term reproducibility of diffusion and oxygenation parameters in renal allograft recipients with stable renal allograft function compared to healthy native kidneys using DWI and BOLD MRI [1]. These two noninvasive functional techniques appeared to be feasible and reproducible in patients with renal allografts. Except for one very recent paper [2] thi...

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ژورنال

عنوان ژورنال: BMC Nephrology

سال: 2018

ISSN: 1471-2369

DOI: 10.1186/s12882-018-0874-9